Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What does plaquenil do to eyes Plaquenil and biaxin for lyme disease Chloroquine proguanil antimalarial Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Hydroxychloroquine Plaquenil is not a new therapy. It has been used in rheumatology for decades and it's proven a very useful medication. Division of Rheumatology, Department of Internal Medicine, and Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil pigmentation treatment Hydroxychloroquine induced cutaneous pigmentation a unique pattern., Plaquenil Pigmentation - BJC Health Extraerythrocytic malria and chloroquineAralen dosePlaquenil drug reviewsMichael marmor plaquenil dec 2015Chloroquine-treated case of plasmodium vivax Chloroquine and hydroxychloroquine. Chemical formula of hydroxychloroquine sulfate commonly known by its old brand-name Plaquenil were first used to treat malaria, but the malaria-causing organism soon became resistant to them. However, during the treatment of patients with malaria who also had lupus, it was noted that their skin rashes improved. Plaquenil Use in Autoimmune Diseases. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Hydroxychloroquine Plaquenil. There is currently no consensus about treatment for lichen planus pigmentosus LPP. Management includes avoiding things that make it worse in each case, such as sun exposure or friction in body folds via weight loss or wearing loose clothing. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B. There was no pigmentation at other body sites. Antimalarial agents are one of the most commonly prescribed drugs for the treatment of autoimmune diseases, including rheumatoid arthritis RA. Hydroxychloroquine HCQ has long‐term treatment benefits in RA.