In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Side effects of chloroquine ncbi Plaquenil et pilule Lysosomal swelling by chloroquine Focus on Eyes Long-term Plaquenil intake can affect your vision by Dr. Juan Carlos de Rivero Vaccari and Dr. Frederick Ho, Special to FLORIDA TODAY Plaquenil, or hydroxychloroquine, is an anti-malaria medication that is commonly used to treat autoimmune disorders like lupus or rheumatoid arthritis. I have been on plaquenil for a while now and have started to have blurred vision. I have been to my eye doc. twice and all tests are normal. Should I continue to take it, I know that it can cause eye problems but my doc. says that it is very rare. Patients using plaquenil may experience important but rare side effects that affect the eyes, including damage to the retina back of the eye, cornea front of the eye, and eyelids. These side effects typically occur on high doses of the medication and increase with duration of use. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. How does plaquenil affect vision What can Hydroxychloroquine Plaquenil do to my eyes?, Plaquenil and blurred vision. Psoriasis from generic plaquenil2d structure of chloroquine Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. What Is Plaquenil? - American Academy of Ophthalmology. Plaquenil - Colorado Springs Eye Clinic. Hydroxychloroquine toxicity - EyeWiki. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or. Plaquenil is a drug that is stored in high concentrations throughout the body and is very slowly eliminated from the body. It is attracted to the retinal pigmented epithelium in the back of the eye the retina. Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell.