It hasnt helped my pain from rheumatoid oh but my hair is falling out ,isnt that lovely! Besides being in pain I can look at how ugly I am now with all my hair falling its just a horrible way to feel,, specially being female to lose your hair and be in pain every day! Does plaquenil thin the blood Generic plaquenil cost Plaquenil maculopathy treatment Hydroxychloroquine pulmonary toxicity I really don’t think the Plaquenil causes anxiety. I think that there are other factors that we deal with related to our illnesses that create anxiety. For example, we over think the illness and ruminate the situation we are in. This leads to other areas of our life suffering. Outward effects of the disease or its treatment. Visible problems such as a facial rash or weight gain from corticosteroids used to treat lupus can affect your physical appearance and self-esteem. Work and activity limitations. Pain, fatigue, and other symptoms can make it difficult to do things you once enjoyed. Sickmama - so very sorry to hear about your worsening moods and depression/anxiety. I can only speak for myself and my personal experience. Plaquenil has helped me on many levels on many days. I think, for me, anyway, the depression and anxiety I often feel is due to the autoimmune issues/sjogrens. 😢😞Taking plaquenil gave me moderate relief from the joint pain. RA sucks and so does all the medication that they come up with ,,were guinea pigs!! Plaquenil and depression and anxiety Plaquenil Side Effects Common, Severe, Long Term -, Lupus and Mental Health Concerns Ra and plaquenilChloroquin for aquarium Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs. Pinho de Oliveira Ribeiro N1, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC. Anxiety, depression and suicidal ideation in patients with.. Plaquenil causing mood changes and depression?. Antidepressants Johns Hopkins Lupus Center. Plaquenil and Depression/Anxiety. I was diagnosed with Sjogren’s a year ago Early Sjogren’s Panel by the doctor I see for Ehlers-Danlos Syndrome. I started at a very low dose- 100mg per day 1/2 of a 200 mg tablet, in addition to a small dose of modafinil I was taking for fatigue, which is my worst symptom. Both the cardiologist and my pcp think that my high heart rate was caused by extreme stress and anxiety, and that it's not the medicine. My rheumy didn't necessarily agree, but he seems to think it's highly unlikely that the plaquenil is causing the tachycardia. He doesn't think that it was caused by a flare based on the normality of my tests. Major Depression is #139 concern in Plaquenil discussions. Plaquenil is an arthritis medication and an anti infectious agent. Uses Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications.