One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine sulfate 200 mg oral tablet verified Plaquenil mechanism of action arthritis Chloroquine cancer patients Plaquenil leaky gut A 53-year-old female with a complaint of something "funny" with her vision. The possibility of hydroxychloroquine toxicity was entertained, although clinical evidence was not found. Color vision testing and funduscopic examination were normal. A full field electroretinogram was normal, but foveal cone electroretinograms were reduced bilaterally. Apr 10, 2019 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Mar 01, 2011 Other tests may be considered as well, but are generally insufficiently sensitive to detect early evidence of hydroxychloroquine toxicity. These tests include color fundus photography, fluorescein angiography, time-domain OCT, full-field ERG, Amsler grid testing, color vision testing, and electro-oculography. Counseling. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Color dx test in plaquenil toxicity Reimbursement for Extended Color Vision Testing Solutions LV., Plaquenil Uses, Dosage & Side Effects - Hydroxychloroquine pill identification 347Hydroxychloroquine lose eye sightDoes lansoprazole interact with plaquenil Plaquenil Screening Traditionally Baseline macula photos Color vision testing Amsler grid 10-2 Visual fields Yearly exams Revised Recommendations on Screening for PlaquenilToxicity • Amslergrid testing removed as an acceptable screening technique – NOT equivalent to threshold VF testing • Strongly advised that 10-2 VF screening be Optical Coherence Tomography OCT The Origins of the OCT. New Screening Guidelines for Hydroxychloroquine Toxicity. Chloroquine and Hydroxychloroquine Maculopathy Case.. Researchers suggest that one central point in both eyes indicates toxicity and one should have a low threshold with regards to any defects. 19 The misinterpreted visual field defect using the larger testing strategies could potentially delay the diagnosis of Plaquenil toxicity resulting in irreversible vision loss. Due to the possibility of. Nov 18, 2011 Keywords hydroxychloroquine toxicity, Plaquenil, toxic maculopathy, Humphrey visual field, retinal toxicity, automated perimetry Introduction Misinterpretation of Humphrey visual field HVF findings in patients utilizing hydroxychloroquine HCQ can lead to delay in diagnosis of retinal toxicity. Aug 29, 2014 Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases.