While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I was on this hydroxychloroquine for 6 months and then suddenly developed severe itching (burning like sensation, worse than any itch I have ever had) and rash that went from my neck to my feet. Plaquenil vision changes Chloroquine phosphate 250 mg Sjӧgren’s Syndrome and Pregnancy. By Mary Anne Dunkin. In rare cases, the antibodies are associated with congenital heart block, an abnormality of the rate or rhythm of the baby’s heart, which can begin in the womb. Effect of pregnancy on Sjogren’s For many women, Sjӧgren’s syndrome worsens during pregnancy and/or after. New Treatment Guidelines for Sjo¨gren’s Disease 533 all methodology elements, including protocol worksheets, data extraction tables, and literature search terms. Pregnant women who have autoimmune diseases, such as lupus or Sjogren’s syndrome, are at an increased risk of having a baby with congenital heart block. Antibodies produced by the pregnant woman’s body in response to the autoimmune disease can cross the placenta, damage to the heart of the fetus, and lead to congenital heart block. But for women with Sjӧgren’s syndrome the excitement can be tempered by concerns related to her disease: Will Sjӧgren’s affect my baby’s development? Will Sjӧgren’s complicate my delivery or affect my ability to breast feed or take care of my child? The nine months of pregnancy can be among the most exciting of any woman’s life. Sjogren's pregnancy heart block hydroxychloroquine Plaquenil A Possible Treatment To Congenital Heart Block., New Treatment Guidelines for SjOgren's Disease Normal dosage daily for plaquenilWhat antihistamines can be taken with plaquenilRa medication hydroxychloroquineMethotrexate plaquenil alcohol Hydroxychloroquine Plaquenil® Hydroxychloroquine can be safely continued during pregnancy. It is commonly used to prevent lupus flares and improve the outcome for mothers with lupus kidney disease.7,8 In fact, women who discontinue hydroxychloroquine during pregnancy are more likely to have exacerbation of lupus disease activity and. Things You Didn't Know about Lupus & Pregnancy. Complete Heart Block Cincinnati Fetal Center.. Preventive Approach to Congenital Heart Block With.. Congenital heart block is a rare complication of pregnancy associated with Sjögren Syndrome that may result in the death of the foetus or infant, or the need for pacing in the newborn or at a later stage. Yang CH, Chen JY, Lee SC, Luo SF. Successful preventive treatment of congenital heart block during pregnancy in a woman with systemic lupus Erythematosus and anti-Sjogren’s syndrome A/Ro antibody. J Microbiol Immunol Infect. 2005; 5–9. Could taking hydroxychloroquine help prevent pregnancy complications? Hydroxychloroquine may benefit pregnancies by reducing active disease of lupus. Hydroxychloroquine may also reduce the chance for a baby to be born with a specific heart conduction problem, called congenital heart block. More studies are needed to understand if hydroxychloroquine helps prevent pregnancy complications.