It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and heart disease Dandelion root and plaquenil Plaquenil isn't known for causing insomnia. It is also a drug that stays in your system for a long time and takes a long time getting IN to your system. It takes 3-5 months to work and just as long to get out of your system. When you started the Plaquenil, how long did it take until you started having insomnia? Sleeping can be deceptive. Part of living with lupus is knowing that your body lives outside of the norm. It means accepting that, for the most part, you have no predictable sleeping pattern, and if you should be lucky enough to regulate one, it’s pretty messed up. Living with lupus means you don’t live on the same. Without a clear medical cause, it’s easy to chalk it up to everyday stress — however, the culprit could be hiding in your medicine cabinet. Chronic conditions aside, insomnia is also a side effect of a variety of medication. The following list from the AARP contains some of the most commonly prescribed drugs known to disturb sleep patterns. 1. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Can plaquenil cause insomnia PLAQUENIL Side Effects, Reviews by Patients -, Lupus-Induced Insomnia and a Feeling of Isolation Plaquenil and low blood sugarChloroquine treatment and virus infection Plaquenil doesn't usually cause insomnia. It is most likely something else, such as prednisone if you're taking it or anxiety. Insomnia is a common complaint for people with Lupus, some as a result of the steroids and some from general stress of the disease. Lupus is a difficult diagnosis to handle and can really make it difficult to fall asleep. Started taking Plaquenil for Lupus and now I can't sleep. Any ideas.. Medications That Can Cause Insomnia and. - Medical Daily. When best time of day to take plaquenil? - LUPUS UK. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil and Insomnia - from FDA reports Summary Insomnia is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. Does plaquenil cause insomnia? I've been taking it for weeks, I take one in the morning, one in the evening. I have not slept for 3 days straight. I thought my ambien wasn't working anymore, but I took 2 last night plus a tylenol PM, and not a wink of sleep.