One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil 3 times a week Aralen generic name Hydroxychloroquine sulfate molecular weight Dence of hydroxychloroquine maculopathy. Table. Clinical, High-Speed Ultra–High-Resolution Optical Coherence Tomography, and Multifocal Electroretinogram Findings From Patients Receiving Hydroxychloroquine Patient No./ Age, y Hydroxychloroquine Dosage, mg/d Diagnosis Treatment, y Symptoms Visual Acuity, OD, OS Color Vision Visual Fields mfERG. Click to email this to a friend Opens in new window Click to share on Twitter Opens in new window Click to share on Pocket Opens in new window Optical coherence tomography based microangiography findings in hydroxychloroquine toxicity Optical coherence tomography based microangiography OMAG is a new, non-invasive imaging modality capable of providing three dimentional 3D retinal and choroidal microvascular maps without a need for exogenous dye. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil toxicity oct findings Hydroxychloroquine toxicity - EyeWiki, Plaquenil Toxicity - OCTMD Do i need a prescription for hydroxychloroquine sulfate 200 mgHow does chloroquine workHistory of hydroxychloroquine Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the findings are normal. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS. Optical coherence tomography based microangiography findings.. Hydroxychloroquine-related retinal toxicity Rheumatology.. Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Hydroxychloroquine Retinal Toxicity. Figure 1. Ocular findings of A pericentral pattern, B mixed pattern, and C parafoveal pattern of hydroxychloroquine retinal toxicity. A Top to bottom Superior field loss is located peripherally in pattern deviation plot 10-2 visual field. Hydroxychloroquine HCQ has been used for therapy of rheumatologic disorders since the 1950s. Ocular toxicity associated with HCQ use was initially described in the 1960s 1, 2incidence of HCQ retinopathy is estimated at 1 % after consumption of HCQ for 5 years is marked by paracentral and central scotoma and decreased color vision.