It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. History of chloroquine phosphate Plaquenil skin Metoprolol and plaquenil interaction Plaquenil photosensitivity rash cheeks Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. Hydroxychloroquine Sulfate “Plaquenil” in Treatment of Rheumatoid Arthritis By E. B. D. HAMILTON AND J. T. SCOTT A controlled therapeutic trial in 41 pa- tients comparing hydroxychloroquine Plaquenil and a placebo tablet showed a small but statistically significant dif- ference in favor of hydroxychloroquine Plaquenil hydroxychloroquine "It started as Palindromic Arthritis, then progressed to full fledged RA with frequent flares attacking my shoulders, elbows, wrists, knees and even my jaw. Most attacks would severely limit my physical abilities. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil arthritis treatment DMARDs for Treating Rheumatoid Arthritis, Hydroxychloroquine sulfate â Plaquenilâ in treatment of. Comparable drug to plaquenilPlaquenil detoxingPlaquenil for sjogren& 39 Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Hydroxychloroquine Plaquenil. Hydroxychloroquine User Reviews for Rheumatoid Arthritis.. Plaquenil vs. Rheumatrex, Trexall Prescription Treatment for.. Treatment. Arthritis treatment focuses on relieving symptoms and improving joint function. You may need to try several different treatments, or combinations of treatments, before you determine what works best for you. Medications. The medications used to treat arthritis vary depending on the type of arthritis. Commonly used arthritis. Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation. When treating lupus or arthritis, Plaquenil is usually given daily for several weeks or months. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 months of treatment. While using Plaquenil, you may need frequent blood tests and vision exams.