One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil safe during pregnancy Taking two plaquenil instead of 1.5 Non aqueous titration of chloroquine phosphate The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy. Jun 13, 2019 Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Current AAO guidelines do not specifically address dosing in obese patients. AAO also recommends baseline screening for retinal toxicity and annual screening beginning after 5 years of use or sooner if major risk factors are present Marmor AAO 2016. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Aao guidelines for plaquenil Rx Side Effects New Plaquenil Guidelines and More - American., What Is Plaquenil? - American Academy of Ophthalmology Plaquenil weightMethotrexate vs plaquenil for lupusHydroxychloroquine multiple sclerosisAct chloroquine and arte sunate Apr 20, 2011 In 2002, the American Academy of Ophthalmology AAO established ocular examination guidelines for screening patients on Plaquenil therapy. Testing included a comprehensive eye exam that consisted of an assessment of the posterior segment with careful evaluation of associated macular changes or signs of retinal disease. 4 Baseline fundus photography was considered as an optional test. New Plaquenil Guidelines. Hydroxychloroquine Professional Patient Advice -. PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Jun 14, 2017 Do you know the current screening recommendations for patients on Plaquenil? Which tests should you choose and when? Risk factors for toxicity are high dose, long duration, renal disease and tamoxifen. If you are coming to the OA July Scientific Meeting July 29th Red Hill, you will hear more about Plaquenil toxicity. Dr. Corte provides a quick reference guide based on the AAO's updated screening guidelines for chloroquine and hydroxychloroquine Plaquenil retinopathy. As optometrists, it is important that we are aware of the possible ocular complications that can occur from the use of high risk medications. Mar 01, 2011 The new guidelines recommend 10-2 automated perimetry, plus at least one of SD-OCT, FAF, or mfERG if they are available. These tests should be performed at baseline and at each subsequent evaluation. Other tests may be considered as well, but are generally insufficiently sensitive to detect early evidence of hydroxychloroquine toxicity.