Retinal thinning in plaquenil toxicity

Discussion in 'Canadian Drug' started by baidach, 06-Mar-2020.

  1. IboCats Moderator

    Retinal thinning in plaquenil toxicity


    Additionally, another exception occurred while executing the custom error page for the first exception. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects.

    Chloroquine antimalarial Hydroxychloroquine for lupus side effects Plaquenil and low dose naltrexone

    In particular, chloroquine and hydroxychloroquine Plaquenil are two such medications, with the potential for retinal toxicity. Given that the retinal damage from these medications is largely irreversible, screening by a retinal specialist is critical to detect early retinal toxicity to try and limit the extent of visual loss. Typically, cases of HCQ toxicity may demonstrate parafoveal thinning and loss of the ellipsoid zone, with preservation of the foveal architecture — creating the “flying saucer” shape Figures 1 and 2. Advanced cases may present with loss of the ellipsoid zone in the foveal area and also widespread diffuse thinning of the outer retinal. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have

    Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Retinal thinning in plaquenil toxicity

    Hydroxychloroquine Plaquenil Toxicity and Recommendations., Retinal Physician - Hydroxychloroquine Maculopathy An.

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  6. Nov 01, 2015 Typically, cases of HCQ toxicity may demonstrate parafoveal thinning and loss of the ellipsoid zone, with preservation of the foveal architecture — creating the “flying saucer” shape Figures 1 and 2. Advanced cases may present with loss of the ellipsoid zone in the foveal area and also widespread diffuse thinning of the outer retinal.

    • Retinal Physician - Hydroxychloroquine Maculopathy An Update..
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    The junction remains in the fovea white arrow. When this thinning is translated into an OCT map, a bulls-eye pattern of thinning is manifested, as shown in the image entitled "Time Domain OCT Map in Hydroxychloroquine Toxicity". The patient shown here is the same one shown in the image "Asymmetric Hydroxychloroquine Plaquenil Retinal Toxicity". Ocular findings of HCQ retinal toxicity as detected by various screening modalities. A female patient was diagnosed with HCQ retinal toxicity at the age of 53 years, having taken HCQ for 12 years at 400 mg/day. She was not obese and had no additional risk factors for toxicity. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.

     
  7. Jazzman Well-Known Member

    Applies to chloroquine: oral tablet Along with its needed effects, chloroquine may cause some unwanted effects. Chloroquine - Wikipedia WHO Model Prescribing Information Drugs Used in Parasitic Diseases. Chloroquine Side Effects Common, Severe, Long Term -
     
  8. ZelAnton User

    Plaquinal side effects? - Lupus - Inspire I'm new to lupus dx'd 3 years ago and I cannot decipher between which AI is flaring. I've just recently started plaquenil, one of my 14 pills + pain meds each day, but am so scared of the side effects! So far it's been ok, but mood changes, blurred vision w/brand new glasses and anxiety have resurfaced.

    The Risk of Retinal Toxicity with Plaquenil
     
  9. MX3000 New Member

    Plaquenil Uses, Dosage & Side Effects - Plaquenil side effects. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.

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