Additionally, another exception occurred while executing the custom error page for the first exception. Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain). Chloroquine drug Is there a drug interaction between ibuprofen and plaquenil Plaquenil treatment for rheumatoid arthritis Conclusions Chloroquine is not significantly ototoxic when administered in regular doses for treatment of uncomplicated malaria. The ototoxic effects of chloroquine which are rarely encountered are fully reversible. Keywords ototoxicity, chloroquine, malaria. I. Introduction hloroquine is a drug with wide spread clinical applications. Ototoxicity at therapeutic doses is limited Aminoglycosidic antibiotics e.g. streptomycin, gentamycin and some other antibiotics e.g. tetracyclines, Loop diuretics* e.g. furosemide, ethacrynic acid Certain analgesics* and antipyretics* salicylates, quinine, chloroquine Ototoxic Medicines Ototoxic medicine. Some medications could potentially cause damage to your hearing, or aggravate an already existing problem. It is important that you, the patient, take responsibility in knowing which drugs you should try to avoid. The parts of the brain that receive hearing and balance information from the inner ear can also be affected by poison, but this is not technically considered ototoxicity and won’t be covered in this information sheet. Because the inner ear is involved in both hearing and balance, ototoxicity can result in disturbances of either or both of these senses. Chloroquine ototoxicity Chloroquine Disease Interactions -, Preventing Hearing Loss Caused by Chemical Ototoxicity and Noise Exposure Avastin hydroxychloroquine Ototoxic Drugs The following list contains drugs that can have a temporary or permanent effect on hearing such as hearing loss or tinnitus. They were identified through the reading of Dr. Susan Kunkel from the Poison Center at the University of New Mexico College of Pharmacy where she is a Toxicology Fellow. Ototoxic Drugs Drugs That Cause Tinnitus Tinnitus Talk.. American Ear Hearing and Audiology LLC - Ototoxic Medications List. Ototoxic Medications Ringing Ears Tinnitus. Chloroquine is related chemically to quinine and, because of this similarity, has been suspected of being an ototoxic drug. 1 It is currently being used for the treatment of malaria, amebiasis, rheumatoid Ototoxicity is typically associated with bilateral high-frequency sensorineural hearing loss and tinnitus. Hearing loss can be temporary but is usually irreversible with most agents. Generally, antibiotic-induced ototoxicity is bilaterally symmetrical, but it can be asymmetrical. Chloroquine CQ, a 4-aminoquinoline drug, has been largely used for the treatment of rheumatoid arthritis and other connective tissue diseases. Besides the well-known retinal toxicity, its use has been suspected of be associated to ototoxicity. Some reports have described mainly sensorineural hearing loss, tinnitus, sense of imbalance, and cochleovestibular manifestations. Differently from.