Resistance to currently available antimalarial drugs has been confirmed in only two of the four human malaria parasite species, first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted. Dry skin from plaquenil Is plaquenil safer than methotrexate Sudden blurry vision with plaquenil have floaters Plaquenil blurry vision reviews Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious Apr 01, 2017 Chloroquine was banned as a first line treatment drug for malaria in Nigeria in 2005. The decision, based on the recommendation of the World Health Organisation, was taken by the Federal Ministry. The agency's director-general, Mojisola Adeyeye, urged Nigerians to desist from using chloroquine as an anti-malaria drug because of the resistance that has been proven to develop in the past. Although resistance to these drugs tends to be much less widespread geographically, in some areas of the world, the impact of multi-drug resistant malaria can be extensive. Has also developed resistance to nearly all of the other currently available antimalarial drugs, such as sulfadoxine/pyrimethamine, mefloquine, halofantrine, and quinine. Nigeria malaria chloroquine resistance Chloroquine - FDA prescribing information, side effects., INVESTIGATION Eleven years after ban. - Premium Times Nigeria Malaria medicine hydroxychloroquineEye plaquenil screeniing May 01, 2018 Unchecked, insecticide resistance could lead to a substantial increase in malaria incidence and mortality. The global malaria community and for that matter, Nigeria, needs to take urgent action to prevent an increase in insecticide resistance, and to maintain the effectiveness of existing vector-control interventions. MALARIA Resistance threatens success of mosquito nets in Nigeria. Coronavirus Chloroquine not approved, NCDC warns.. Chloroquine-Resistant Malaria The Journal of Infectious.. Chloroquine resistant P. falciparum was associated with specific point mutations in the P. falciparum chloroquine-resistant transporter pfcrt and Plasmodium falciparum multi-drug resistant Pfmdr- 1 genes among children aged 1-12 years in Ibadan, Nigeria. Facts about malaria in Nigeria. In Nigeria, malaria is endemic. Accounts for 60% of outpatient visits. Responsible for 30% of under-5 mortality. Resurgence of malaria is observed in recent times. Resurgence due to increasing resistance to chloroquine & sulfadoxine-pyrimethamine. DRUG RESISTANT MALARIA Chloroquine resistance Chloroquine is ineffective in almost all malaria endemic countries In India chloroquine resistance was first detected in 1973 in Assam. Severe in northeast and southeastern regions of India with high morbidity and mortality.