Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil lethargy Withdrawal from hydroxychloroquine Calcium chloroquine Chloroquine tablet Your toes also may sting, burn or feel numb. Morton's neuroma is a painful condition that affects the ball of your foot, most commonly the area between your third and fourth toes. Morton's neuroma may feel as if you are standing on a pebble in your shoe or on a fold in your sock. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil also called How effective is Plaquenil for Osteoarthritis by duration., Hydroxychloroquine Plaquenil Plaquenil positive reviews Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination therapy with other DMARDs for moderate to severe disease. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil Hydroxychloroquine Sulfate. HYDROXYCHLOROQUINE SULFATE 200MG FILM-COATED TABLETS. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work.