Chloroquine in early pregnancy

Discussion in 'Canadian Pharmacies' started by Ne1son, 25-Feb-2020.

  1. SoftMaster New Member

    Chloroquine in early pregnancy


    This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus.

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    More research is therefore ideally required to confirm that use of chloroquine at this stage of pregnancy is not harmful. However, malaria infection during early pregnancy is itself known to increase the chance of miscarriage, and any possible risk from taking chloroquine is likely to be less than the risks posed to both mother and baby by malaria. It appears to be safe for use during pregnancy. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. It is available as a generic medication. For pregnant women diagnosed with uncomplicated malaria caused by chloroquine-resistant P. falciparum infection, women in the second and third trimesters can be treated with artemether-lumfantrine, and for all trimesters, mefloquine or a combination of quinine sulfate and clindamycin is recommended. Quinine treatment should continue for 7 days for infections acquired in Southeast Asia and for 3 days for infections acquired elsewhere; clindamycin treatment should continue for 7 days.

    For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®.

    Chloroquine in early pregnancy

    Update New Recommendations for Mefloquine Use in Pregnancy, Chloroquine - Wikipedia

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  5. According to the Centers for Disease Control and Prevention CDC, chloroquine is considered safe to use during pregnancy. Tell your doctor if you're pregnant or might become pregnant while taking.

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    In a cohort of US government employee taking chloroquine 300 mg weekly as prophylaxis throughout pregnancy in 1969-1978, the prevalence of new- borns with congenital abnormality 1.2%, 2/169. Pregnant women are advised to avoid travel to countries where there is elevated risk of contracting malaria. 2,3 For pregnant individuals who still choose to or must travel to malaria-endemic areas where there is chloroquine resistance, currently none of the available prophylactic drugs are recommended in early pregnancy. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2

     
  6. brian New Member

    Some side effects may occur that usually do not need medical attention. Plaquenil Side Effects - GoodRx Will you have Fatigue with Plaquenil - eHealthMe Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.
     
  7. prosei XenForo Moderator

    Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks.

    Compare Plaquenil vs Chloroquine -
     
  8. Bizon Well-Known Member

    Plaquenil and Eczema - Reviews - Treato The cream my doctor gave me for my face is, Elidel primecrolimus cream 1%. He gave me this tiny free sample tube, that I used only a couple of days and it cleared.told me it was pretty expensive and that I definately shouldn t use the Clobetasol on my face, because it is too strong for the thinner skin of your face.

    Has anyone experienced plaquenil toxicity with damage to eyes?