Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Missed dose of plaquenil Plaquenil for lyme Hydroxychloroquine and allergy testing Plaquenil arthritis medication Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil tablets side effects Plaquenil Hydroxychloroquine - Side Effects, Dosage., Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Natural alternatives to plaquenilSudden blurry vision with plaquenil have floatersPlaquenil lupus weight lossPlaquenil tabletas Plaquenil Side Effects by Likelihood and Severity. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil Hydroxychloroquine Side effects, Images, Uses, Dosage.. Feb 19, 2020 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.