I would think the drug has aggravated a pre-existing condition. There may be another drug that would not cause your GERD. Can you take tylenol with plaquenil Chloroquine-primaquine-phosphate. Plaquenil keep you awake I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction. Popular Heartburn Meds Can Have. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. It's recommended you wait at least four hours after taking hydroxychloroquine before you take an indigestion remedy. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil is the brand name for the prescription drug hydroxychloroquine. What can i take for heartburn with plaquenil Gastroscopy, have to stop medication 10 days before? - UK., Plaquenil oral Reviews and User Ratings Effectiveness. Chloroquine overdose amountBest malaria medication for chloroquine resistant malariaWhat eye exam is needed for plaquenil In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Side-effects, uses, time to work. Plaquenil I have heard quite a few. - PBC Foundation. It might be a bit of heartburn or gastritis. Make sure though to wait 2 hrs before and 2hrs after taking the plaquenil to take an antacid. Watch that sun. I find I feel worse when I've had too much of it. I'm prone to itching like crazy after too much sun. Are you using a broad spectrum sunscreen and UV protective clothing hat too? At any rate, what I'm getting at is if she is on 2 pills a day she may be able to split the dose am and pm, or take it all in one lump sum -- check with your doc on whether timing is important, and if not maybe adjusting her intake can help with the tummy troubles. Plaq takes 2 - 6 months to become effective. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.