Please review the following URL and make sure that it is spelled correctly. Plaquenil, hydroxychloroquine (HCQ), is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory and autoimmune diseases. Quinine sulfate allergy is it okay to take plaquenil Who should not take plaquenil Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Apr 20, 2011 Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Plaquenil eye issues RA and Your Eyes Complications Rheumatoid Arthritis., New Plaquenil Guidelines Macular degeneration from plaquenilPlaquenil and stomach ulcersG6pd plaquenil It is attracted to the retinal pigmented epithelium in the back of the eye the retina. Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. Also, Plaquenil may have various systemic side effects that are not related to the eyes. PLAQUENIL hydroxychloroquine and the Eye Westford. Common and Rare Side Effects for Plaquenil Oral. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil is taken by mouth with food or milk to prevent stomach problems. When taking this medication, some patients may experience upset stomach, nausea, loss of appetite, headaches or dizziness. Sometimes, taking high doses or long-term treatment of Plaquenil can lead to vision problems. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. An eye exam is recommended at the start of treatment to detect any existing vision problems; follow-up tests are needed to catch retinal damage in the earliest stages, before symptoms appear. If found later, damage to the eye may be irreversible, even if the medication is stopped.