Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil arthritis treatment Plaquenil storage water or fat soluble Plaquenil can cause serious vision problems that aren't always reversible. Tell your doctor immediately if you notice any changes in vision or if you've ever had vision changes while taking. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause headaches The Risk of Retinal Toxicity with Plaquenil, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil and heart diseasePlaquenil cost irelandHydroxychloroquine for autoimmunePlaquenil frontal fibrosing alopecia Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. Common culprits and what you can do. Pharmacy and Medication Tips. Things to remember when you fill your prescription. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. For the four years that I took the drug.