The degree of muscle weakness involved in myasthenia gravis varies greatly among individuals. The onset of the disorder may be sudden, and symptoms often are not immediately recognized as myasthenia gravis. Plaquenil special considerations Hydroxychloroquine copay assistance program Hero study hydroxychloroquine Plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug DMARD. A condition called myasthenia gravis. BOTH systemic lupus and myasthenia gravis are suspected of having an "auto-immune" etiology. Therefore, their association in the same patient is of interest, and the purpose of this paper is to report the 15th patient known to have both diseases. Report of a Case A 28-year-old woman was seen in April 1962. The next day they were sore like I had exercised at the gym. I also feel like I have Myasthenia Gravis like symptoms, such as when combing my hair my arms get extremely fatigued. If it's the Plaquenil causing this, will it stop once I quit taking the Plaquenil? I have an EMG scheduled, will the emg pick up anything if the plaquenil is causing it? top The hallmark of myasthenia gravis is muscle weakness that worsens after periods of activity and improves after periods of rest. Certain muscles such as those that control eye and eyelid movement, facial expression, chewing, talking, and swallowing are often (but not always) involved in the disorder. Plaquenil and myasthenia gravis PDF Myasthenia gravis due to hydroxychloroquine, Myasthenia Gravis and Systemic Lupus Erythematosus JAMA Neurology. Difference between hydroxychloroquine and chloroquineHydroxychloroquine sulfate tabs 200mg and eczemaPlaquenil dry mouth MYASTHENIA GRAVIS MEDICATIONS TO USE WITH CAUTION This list is not comprehensive and these drugs may affect each person differently. Please check with your neurologist before surgeries or adding medications. Key 1 - Contraindicated. Avoid in MG patients, even if disease is controlled. 2 - Likely to worsen MG. MYASTHENIA GRAVIS MEDICATIONS TO USE WITH CAUTION. Possible side effects of Plaquenil - Neurology - MedHelp. Myasthenia gravis - Symptoms and causes - Mayo Clinic. Definitely talk to a neurologist about Myasthenia Gravis MG. That’s where all my issues started-double vision and extreme extremity weakness when I was 17 after the birth of my first child 28, I was diagnosed with Sjogrens Syndrome and had major flare ups after the birth of my next two children. There are many drugs that have the potential of exacerbating myasthenia gravis. These include various antibiotics, heart medications, magnesium, etc. Plaquenil does have the risk of impairing neuro-muscular transmission and may worsen/exacerbate myasthenic symptoms. I would suggest you discuss your concerns with your rheumatologist. Myasthenia gravis MG is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest.