Many people find that they have unexplained bruising on legs and want to know what causes bruises to appear for no apparent reason. Some people also bruise more easily than others and a seemingly insignificant knock may leave a black and blue dark patch on their skin. Benlysta and plaquenil Hydroxychloroquine drug interactions Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Random bruising on your legs as well as on other body parts can cause unsightly skin discoloration as a result of a mild trauma or injury. Many people find that they have unexplained bruising on legs and want to know what causes bruises to appear for no apparent reason. Bruising is common with long term steroid use. Spotted Trout Syndrome I like to call it. How did that get there? A common comment from mates. As long as the bruises heal all good. If bruises linger or enlarge best to go to doctor to sort as an infection can occur. Be careful. Be well. On on on. For example, being in the sun too long, aging, or a vitamin deficiency can weaken small blood vessels near the skin’s surface. Random or unexplained bruising on legs can happen for a number of reasons. Plaquenil and unexplained bruising Signs unexplained bruising may be worrisome Shine365 from., Unexplained Bruising on Your Body Causes and Treatments Sam-e hydroxychloroquineAao guidelines for plaquenilDoes plaquenil interact with gerdDoes plaquenil cause fatigue Are you using NSAIDs for pain? I had to stop them because of unexplained bruising. The Plaquenil has never caused me any bruising but the NSAIDs apparently did. The bruises were quite alarming. I'm now on Tramadol and paracetamol as opposed to Naproxen or Diclofenac. I liked Naproxen but have been told its a no no. Take care - Scottie Plaquenil and bruising? NOW ALL OVER BODY RASH!. Bruising I keep getting bruises appear on. - HealthUnlocked. Random Bruising 13 Possible Causes Excluding Obvious Injury. Oct 22, 2019 Low blood cell counts have happened with Plaquenil hydroxychloroquine. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Call your doctor right away if you have signs of infection like fever, chills, or sore throat; any unexplained bruising or bleeding; or if you feel very tired or weak. Nov 25, 2015 8 reasons for unexplained bruises on your body Do you bruise in places that you don’t even remember bumping or hurting, and the bruise doesn’t go away for months together? Read more about what. Unexplained Pain Could Those Aches and Fatigue Be an Autoimmune Disease. Easy bruising; Anxiety or depression;. For patients with mild symptoms, the anti-malarial drug Plaquenil can ease.