Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Chloroquine off target effects Target of chloroquine Side effects after stopping plaquenil Plaquenil dry mouth Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I. Macular Society Eye screening for patients taking hydroxychloroquine Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. It was previously used in the treatment and Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Management of plaquenil maculopathy Plaquenil oral Reviews and User Ratings Effectiveness., Chloroquine And Hydroxychloroquine Toxicity - StatPearls. Plaquenil for skin rashHydroxychloroquine wiki Besides Plaquenil and Chloroquine, what other drug is known to cause Bull's eye Maculopathy? HVF 24-2 or 30-2 instead of 10-2 because damage tends to be further from the fovea Do SD-OCT scans outside of fovea too- FAF is a good choice Ocular Side effects of Oral Medications Flashcards Quizlet. Eye screening for patients taking hydroxychloroquine Plaquenil. Hydroxychloroquine retinopathy Eye. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. The drug-induced maculopathy is associated with the following risk factors Cumulative dose level of 1,000 grams of plaquenil. Patients with existing retinal or macular disease.