Prophylaxis for chloroquine resistant malaria

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  1. 1kjhnvkhvjjk5 XenForo Moderator

    Prophylaxis for chloroquine resistant malaria


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Oct 01, 2018 Chloroquine-Resistant Malaria Chloroquine phosphate tablets are not effective against Chloroquine-or hydroxyChloroquine-resistant strains of Plasmodium species see CLINICAL PHARMACOLOGY, Microbiology. Chloroquine resistance is widespread in P. falciparum and is reported in P. vivax. Before using Chloroquine for prophylaxis, it should be. Malaria infection associated with travel. Center for Global Health Division of Parasitic Diseases and Malaria. Who can take chloroquine? Chloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant. women and nursing mothers. Who should not take chloroquine? People with psoriasis should not take. The Lancet CLINICAL PRACTICE Vivax malaria resistant to treatment and prophylaxis with chloroquine G. S. Murphy MD * a * Correspondenceto Dr Gerald S. Murphy, Department of Internal Medicine, Naval Hospital, San Diego, California 92134-5000, USA.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Prophylaxis for chloroquine resistant malaria

    Malaria Prophylaxis. The ABCD of Malaria Prophylaxis., Medicines for the Prevention of Malaria While Traveling.

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  7. For these reasons, and because chloroquine has not been found to have any harmful effects on the fetus when used in the recommended doses for malaria prophylaxis, pregnancy is not a contraindication to malaria prophylaxis with chloroquine or hydroxychloroquine.

    • Malaria ProphylaxisMalaria Site.
    • Vivax malaria resistant to treatment and prophylaxis with..
    • CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria.

    Apr 15, 2002 Chloroquine is the drug of choice for people who travel to these areas; however, resistance to chloroquine is now widespread in all areas of the world where malaria is endemic, but it is still an. In areas where there is chloroquine-resistant malaria, either atovaquone/proguanil Malarone, mefloquine Lariam or doxycycline can be used for prophylaxis. Primaquine is a good alternative, but requires a G-6-PD screening blood test. High prevalence of chloroquine-resistant P. vivax confirmed in Papua New Guinea and Indonesia; 115 143 also reported in Burma Myanmar, India, and Central and South America. 143. Do not use for prevention of malaria in individuals traveling to malarious areas where chloroquine-resistant P. falciparum or chloroquine-resistant P. vivax malaria.

     
  8. murmura User

    Atovaquone/Proguanil (Malarone) Adults: 1 adult tablet daily. Malaria Health Information for International Travel Chloroquine-Resistant Malaria – Medicines for the Prevention of Malaria While Traveling.
     
  9. exebosser Well-Known Member

    Study Shows Methotrexate and Prednisone Combination Therapy Achieves. All patients were started with initial combination therapy that consisted of 25mg/wk methotrexate MTX and 60 mg/day of prednisone tapered to 7.5mg/day over seven weeks. If patients achieved remission after 4 months, they were considered to be in early remission and could taper prednisone down to zero.

    Effects of methotrexate and hydroxychloroquine combination.
     
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