I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. Side effects hydroxychloroquine plaquenil How to bill for following plaquenil retina Who chloroquine and flouroquinolone Plaquenil affect immune system Lupus Support Group Lupus is an auto-immune disease in which the immune system cannot distinguish between threats like viruses and bacteria, and healthy cells and tissue. As a result, the body produces antibodies that inflict cell damage, most commonly targeting joints, skin, kidneys and the nervous system. I took prednisone for a week, & started taking 200mg plaquenil & 2400mg ibuprofen daily, & 50-150mg tramadol as needed for pain. In my experience, the prednisone helped to reduce the excruciating, debilitating joint pain by calming the inflammation, & plaqenil & ibuprofen keep it at bay.the most part. Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. Lupus plaquenil prednisone Prednisone and Plaquenil drug interaction Lupus nephritis - eHealthMe, Plaquenil User Reviews for Systemic Lupus. - Can you take plaquenil before surgeryChloroquine diphosphate intercalator dnaPlaquenil equivalentSickle cell disease hydroxychloroquine thrombosisHydroxychloroquine treats what infx It is hard to draw a deep breath and I’ve had a lot of neck pain with the lung issues. He said that is normal for the pain to radiate to the neck. It should go away with the prednisone I have found that to be true. Plaquenil probably won’t protect you from getting Covid-19, but it should make it less dangerous and shorten the lifespan. Prednisone and Immunosupression lupus. Prednisone and Plaquenil question" Lupus Community - Support Group. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil is an arthritis medication and an anti infectious agent. Prednisone is a steroid. There may be a negative interaction between Plaquenil and alcohol. There may be a negative interaction between Prednisone and alcohol. Compare Plaquenil vs Prednisone head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Plaquenil rated 6.8/10 vs Prednisone rated 7.7/10 in overall patient satisfaction. Risk factors include active lupus erythematosus, maintenance therapy using prednisone dosages of more than 20 mg daily, renal disease and hypertension Increased risk of premature rupture of the.