Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Aralen instructions Chloroquine for malaria infection A multidisciplinary approach is required to care for patients with rheumatoid arthritis RA in the perioperative period. In preparation for surgery, patients must have a cardiovascular risk assessment performed due to the high risk of heart disease in patients with RA. Methotrexate Methotrexate is. Hydroxychloroquine. Methotrexate and plaquenil. now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. i am still in so much pain everyday and hoping for some relieve soon. I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Methotrexate and plaquenil Does anyone take methotrexate and hydroxychloroquine., Methotrexate and plaquenil - Plaquenil mid back painDoes plaquenil reduce swellingChloroquine resistance areas What is Methotrexate? Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. Check the latest outcomes from 354,175 Methotrexate users, or browse all drugs. What is Plaquenil? Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Methotrexate and Plaquenil drug interactions - eHealthMe. Which would you pick and why? - Plaquenil or Methotrexate. Plaquenil vs. Rheumatrex, Trexall Prescription Treatment.. The study is based on hydroxychloroquine sulfate and methotrexate sodium the active ingredients of Plaquenil and Methotrexate, respectively. Other drugs that have the same active ingredients e.g. generic drugs or brand names are also considered. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Taking methotrexate with hydroxychloroquine has not been studied. It may increase your risk of side. Oct 09, 2015 I had a biopsy and my doctor said he believes it is morphea. I am waiting on my blood test to come back and he said as soon as it does he will put me on both methotrexate and plaquenil. The doctor is.