Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. How is chloroquine manufactured Plaquenil generic shortage Find information about common, infrequent and rare side effects of Plaquenil Oral. Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil have to build up in your system Taking Plaquenil for Rheumatoid Arthritis, Anyone on Hydroxychloroquine plaquenil - Autoimmune. Pricing on plaquenil at sam's Plaquenil and its affect on the immune system. I am so confused and in so much pain. My Rheumy started me on Plaquenil 200 mg 1 x day a few months back. After a few weeks I started to feel some pain/joint relief and more energy. Plaquenil and its affect on the immune system DailyStrength. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk. Your body weight will tell your doctor what dose is safe for you. Be sure to notify your ophthalmologist that you are taking this medicine so you can have the correct visual screening tests. Every person starting Plaquenil should have a baseline ophthalmologic exam within the first year, see the section below on How to use Plaquenil for things to ask for during your visit and regular screenings thereafter. I actually am still taking plaquenil, and my rhuemy has told me to skip two days a week of taking them as plaquenil is supposed to build up in your system,and she says after a while that the patient needs to wean off of it.