Chloroquine phopshate usp

Discussion in 'Northwest Pharmaceuticals Canada' started by Niko0766, 08-Mar-2020.

  1. Paustimbimb Well-Known Member

    Chloroquine phopshate usp

    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Dissolve an accurately weighed quantity of USP Chloroquine Phosphate RS in dilute hydrochloric acid 1 in 1000, and dilute quantitatively and stepwise with the same dilute hydrochloric acid to obtain a Standard solution having a known concentration of about 10 µg per mL. Concomitantly determine the absorbances of both solutions in 1-cm cells. Chloroquine Phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. Chloroquine Phosphate Tablets are an antimalarial and amebicidal drug.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine phopshate usp

    Chloroquine phosphate Pharmaceutical Secondary Standard., USP Monographs Chloroquine Phosphate Tablets

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  6. USP Chloroquine phosphate United States Pharmacopeia USP Reference Standard Synonym N 4-7-Chloro-4-quinolinyl-N 1,N 1-dimethyl-1,4-pentanediamine diphosphate salt, Chloroquine diphosphate salt CAS Number 50-63-5. Empirical Formula Hill Notation C 18 H 26 ClN 3 2H 3 PO 4. Molecular Weight 515.86. Beilstein/REAXYS Number 4223142.

    • Chloroquine phosphate United States Pharmacopeia USP..

    USP Chloroquine Phosphate RS determine the absorbances of both solutions at the wavelength Identification— of maximum absorbance at about 343 nm, with a suitable A Dissolve 35 mg in 4 mL of chloroform, and pass through spectrophotometer, using water as the blank. Chloroquine phosphate is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Storage Chloroquine phosphate should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda.

  7. AleZver Moderator

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  8. Lupus -- also called systemic lupus erythematosus, or SLE -- might not have a cure, but it's a highly treatable condition. Safety of Long term use of Hydroxychloroquine Therapy. Plaquenil - does it take long time to work? - Lupus - Inspire PLAQUENIL To Take or Not To Take?" Lupus Community.
  9. mama999 XenForo Moderator

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  10. maxud Well-Known Member

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Feb 19, 2020 PLAQUENIL is not effective against chloroquine or hydroxychloroquine-resistant strains of Plasmodium species see CLINICAL PHARMACOLOGY - Microbiology. PLAQUENIL is not recommended for the treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodium species has not been identified.

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses