Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and methotrexate taken together Chloroquine clinical trials cancer How to reverse the side gastrointestinal side effects of plaquenil Hydroxychloroquine sulfate adverse reactions Diagnosis. There is no specific test to confirm a diagnosis of mild cognitive impairment MCI. Your doctor will decide whether MCI is the most likely cause of your symptoms based on the information you provide and results of various tests that can help clarify the diagnosis. Nov 19, 2019 Cognitive disorder is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 month, also take medication Lyrica, and have Pain. I am new to this connective tissue disease. I have been put on Plaquenil twice a day and Mobic one time a day. I am understanding this Plaquenil can cause you to go blind after a period of time. All I know is the pain is excruciating at times and I am very lethargic and hurt constantly. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Cognative issues plaquenil Plaquenil Uses, Dosage & Side Effects -, Will you have Cognitive disorder with Plaquenil - eHealthMe Pharmacokinetics of chloroquine Learn about multiple sclerosis cognitive impairment from the Cleveland Clinic, such as memory loss, difficulty thinking or multitasking, and other problems. Coronavirus Check here for latest testing information, visitor restrictions + service changes. Multiple Sclerosis & Impaired Thinking - Cleveland Clinic. Connective Tissue Disease Symptoms Treatment & Prognosis.. Plaquenil Side Effects on Your Eyes and Vision. This impairment in intellectual ability has been termed cognitive dysfunction, and has recently become the focus of much interesting research. It is now recognized that cognitive dysfunction is one of the subtler manifestations of “Neuropsychiatric SLE” NPSLE, that is lupus that affects the nervous system, with manifestations that are either neurologic or psychiatric in nature. Can Plaquenil cause Cognitive Problems? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Lupus fog is a general name for the cognitive impairments that often appear with lupus, including concentration and memory problems, confusion, and difficulty expressing yourself.