One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine common name Hydroxychloroquine pregnancy class Does plaquenil have life long effects Plaquenil for crohn's Clinical trials are research studies that involve people. The clinical trials on this list are studying Hydroxychloroquine. All trials on the list are supported by NCI. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical. Monitoring and Preventing Hydroxychloroquine, Plaquenil, Toxicity. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Hydroxychloroquine diagnostic studies routinely Hydroxychloroquine-Induced Retinal Toxicity - American., Monitoring and Preventing Hydroxychloroquine, Plaquenil, Toxicity. Chloroquine calcium phosphate transfectionPlaquenil painful muscle spasms Although hydroxychloroquine retinal toxicity is thought to be rare, recent studies suggest it may have a higher prevalence than previously recognized. A large study examining patients with more than 5 years of HCQ use were evaluated with 10-2 visual fields or spectral-domain optical coherence tomography SD OCT. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine Side Effects Common, Severe, Long Term -. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or. May 26, 2017 Hydroxychloroquine HCQ is frequently used to treat autoimmune diseases, especially systemic lupus erythematosus SLE. Although its exact mechanism of action in autoimmune diseases is not completely understood, we do know that HCQ has many benefits and plays a key role in the management of many diseases. A study of about 200 patients with a history of hydroxychloroquine retinopathy, including 36 Asian patients, found that the pericentral pattern occurred in half the Asian patients but only 2% of the white patients. 31 The mechanism for this finding is unclear, but because pericentral retinopathy spares the macula.