Hydroxychloroquine muscle wasting

Discussion in 'Northwest Pharmacy Canada' started by lexaup, 18-Mar-2020.

  1. Fashion XenForo Moderator

    Hydroxychloroquine muscle wasting


    It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc.

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    I've had a terrible experience with it. Extensive muscle wasting which eventually resulted in a weight loss of about 40% and three near death experiences in approx. 6 years. It's also very bad for your eyes in the long term. Chloroquine and hydroxychloroquine HCQ are commonly prescribed antimalarial agents used for a variety of systemic diseases. HCQ neuromyotoxicity is a rare complication characterized by proximal muscle weakness, normal creatinine kinase levels, and characteristic ultrastructural changes on muscle biopsy of curvilinear body formation. In this. In a study of 350 RA patients in Spain, weakness, muscle atrophy, and muscle inflammation were commonly observed in those suffering from RA Miro, et al, 1996. 4 A detailed research study by Helliwell and Jackson published in 1994 documented RA’s impact on muscle tissue. They concluded, “Although there is significant muscle wasting in RA, it is likely that reduction in strength is also.

    For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting.

    Hydroxychloroquine muscle wasting

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  5. Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups, depressed tendon reflexes, and abnormal nerve conduction, have been reported. Muscle and nerve biopsies have been associated with curvilinear bodies and muscle fiber atrophy with vacuolar changes. Assess muscle strength and deep tendon.

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    I was hospitalized for a week bc I suffered terrible muscle atrophy and weakness and couldn't stand up without collapsing I hit rock bottom on 11/1 and was hospitalized for one week three days ago i crashed and burned also went down 7 pounds since taking it and am 5'6" and now weigh 105 pounds. Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Here we report a case of woman with systemic lupus erythematosus who presented with myopathy after eight months treatment with hydroxychloroquine. Not for administration with other drugs that have potential to prolong QT interval; hydroxychloroquine prolongs QT interval; ventricular arrhythmias and torsades de pointes reported in patients taking hydroxychloroquine. Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups, depressed.

     
  6. x1313 Well-Known Member

    Living with inflammatory bowel disease (IBD) -- including ulcerative colitis and Crohn's disease -- can be painful and embarrassing. Allergic reaction to plaquenil DailyStrength Hydroxychloroquine Side-effects, uses, time to work Plaqunil rash -
     
  7. Rainbow74 Moderator

    Roaming tendonitis anyone? - I've been having periods of excruciating tendon pain, sometimes with massive swelling, for the past few months. It's been almost constant for the past month or so, but 'roaming' is a perfect term for it. last week it was all across the top of one foot and the sole of the other and I was crawling around the house on my knees because I couldn't.

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