I’m still not 100% but my Rhuemy is think Undifferentiated Connective tissue disease which is not the same as Multiple connective tissue disease. I was wondering if there’s anyone on here who has this? Ive found no foundation and almost no awareness on this disease at all.. Hydroxychloroquine gastrointestinal bloating Plaquenil and dental inplants Hydroxychloroquine Plaquenil can treat mild mixed connective tissue disease and might prevent flare-ups. Calcium channel blockers. This category of medications, including nifedipine Procardia and amlodipine Norvasc, help relax the muscles in the walls of your blood vessels and may be used to treat Raynaud's disease. I'm no medical expert and have no training but I think the term undifferentiated connective tissue disease UCTD is similar to use of the term idiopathic for a diagnosis that's not specific. Here are a few articles I found using Google Scholar. Description •Undifferentiated connective tissue disease UCTD is an autoimmune disease that presents similarly to other rheumatic conditions but fails to meet laboratory requirements which indicate a specific disease such as rheumatoid arthritis, systemic lupus erythematous, Sjogren's or scleroderma. I see a lot of mixed info so I’d love to hear experiences, explanations, like anything and everything that anyone knows about this. So if I do have UCTD mine presents itself very similarly to lupus and RA with some Sjorgens similarities too. Ive found no foundation and almost no awareness on this disease at all.. I'm no medical expert and have no training but I think the term undifferentiated connective tissue disease (UCTD) is similar to use of the term idiopathic for a diagnosis that's not specific. I don’t see much awareness for this disease or much information. there's only 2 discussions actually on UCTD and no one seems to really know what it is. from my understanding if I'm diagnosed with UCTD it's because I have Lupus and RA symptoms with some blood test markers of both but the tests aren't conclusive enough… Jump to this post Hi @bunnysammy — I usually go to Google Scholar (https://scholar.google.com/) when I'm trying to find some in depth information or studies on a medical diagnosis or research papers. Undifferentiated connective tissue disease hydroxychloroquine Unidentified Connective Tissue Disease, Undifferentiated Connective Tissue Disease Mayo Clinic. Plaquenil and stomach problems Regarding the treatment of undifferentiated connective tissue disease, there have been no formal scientific studies of specific treatments for undifferentiated connective tissue disease. The treatment selection is typically based on the symptoms presented and a doctor's previous success in prescribing a particular treatment for rheumatic diseases. What Is Undifferentiated Connective Tissue Disease?. Treatment of Undifferentiated Connective Tissue Disease by.. Undifferentiated Connective Tissue disease - Rheumatology.. Undifferentiated connective tissue disease UCTD is an autoimmune disease that can affect several systems in the body. Connective tissue disease CTD is classified as undifferentiated CTD when signs and symptoms are consistent with a CTD, but do not fulfill the diagnostic or classification criteria for one of the previously defined CTDs for example, rheumatoid arthritis or lupus. UCTD and Plaquenil deleted_user 08/28/2012 Finally, I have seen another rheumy for a second opionion, and have received the diagnosis of Undifferentiated Connective Tissue Disease UCTD that could develop in to Lupus. With undifferentiated connective tissue disease, I had excruciating pain for more than a year. Joint and muscle pain, lung pain, numbness in fingers and toes, almost lost a finger, fluid in the lungs - I can't even remember all of the symptoms.