It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Milk thistle and plaquenil Plaquenil cause cushing's Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. When treating lupus or arthritis, hydroxychloroquine is usually given daily for several weeks or months. For. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin with or without fever; red or irritated eyes; or sores in your mouth, throat, nose, or eyes. Preventing malaria Fever that happens while in or after coming back from the malaria area. What are some other side effects of Hydroxychloroquine? Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Fever with hydroxychloroquine Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Indications, Side Effects, Warnings. Plaquenil and tylenol cold and flu severe Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine Uses, Dosage & Side Effects -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. An exception to this is the use of hydroxychloroquine in patients with porphyria cutanea tarda. When used in relatively high doses, hydroxychloroquine can trigger an acute hepatic injury with sudden onset of fever and marked serum enzyme elevations with increased excretion of porphyrins. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Rarely, hydroxychloroquine can lead to anemia in some individuals. This can happen in individuals with a condition known as G6PD deficiency or porphyria. In rare cases, hydroxychloroquine can cause visual changes or loss of vision.