Chloroquine myopathy

Discussion in 'Trusted Online Pharmacy' started by yurandinyo, 08-Mar-2020.

  1. Hmmka Moderator

    Chloroquine myopathy


    Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention.

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    Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Suggestions that chloroquine may also injure peri-pheral nerve and muscle. There are still only a few descriptions of such chloroquine neuropathy or myopathy, and in several of these the drug was used in treating patients with possible or proven collagen diseases. In these latter instances the cause ofthemusclechangeis perhapsopento somedoubt, Although the precise incidence is unknown, drug-induced myopathy is among the most common causes of muscle disease. Drug-induced myopathy ranges from mild myalgias with or without mild weakness to chronic myopathy with severe weakness and to massive rhabdomyolysis with acute renal failure.

    Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine.

    Chloroquine myopathy

    Chloroquine MedlinePlus Drug Information, Chloroquine myopathy

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  5. Chloroquine is an amphiphilic drug structurally simi-lar to chloroquine but with a hydroxylated side chain as its name implies. Both chloroquine and hydroxy-chloroquine have been used in experimental and clin-ical models of GVHD 1,8. It is synergistic with other drugs such as cyclosporine, tacrolimus, and sirolimus 9,10.

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    Respiratory failure associated with HCQ myopathy. Our patient presented with proximal myopathy, respiratory insufficiency, and necrotizing vacuolar myopathy with curvilinear body formation. Her risk factors included her age, white race, and long duration of HCQ use. The differential diagnosis included corticosteroid myopathy and inclusion body. Hydroxychloroquine was noted, in one large prospective study of 119 patients, to have toxic myopathy of 1.2% with a prevalence of 6.7% 2. In that study 111 received chloroquine and 8 received hydroxychloroquine, and interestingly, several patients had “myeloid bodies” spheromembranous bodies in addition to curvilinear bodies on biopsy. Chloroquine myopathy 240102007. Vacuolar myopathy associated with chloroquine, lupus erythematosus and thymoma. Report of a case with unusual mitochondrial changes and lipid accumulation in muscle. Mastaglia FL, Papadimitriou JM, Dawkins RL, Beveridge B J Neurol Sci 1977 Dec;343315-28.

     
  6. Ant0nV New Member

    Plaquenil (sulfato de hidroxicloroquina) es un medicamento utilizado originalmente para prevenir o tratar la malaria. Hydroxychloroquine Oral Route Description and Brand. Hydroxychloroquine MedlinePlus Drug Information Hydroxychloroquine Plaquenil -
     
  7. Polka2009 XenForo Moderator

    The following information is NOT intended to endorse any particular medication. How long did Plaquenil/Hydroxychloroquine take? DailyStrength Taking Plaquenil for Rheumatoid Arthritis Hydroxychloroquine Uses, Dosage & Side Effects -
     
  8. nik_andr Guest

    Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center If your ophthalmologist does find some Plaquenil deposits, s/he will simply request that you stop taking the medication, and you may follow up with your rheumatologist about another advised method of treatment. Unfortunately, retinal damage caused by Aralen may be irreversible, but this medication is rarely prescribed anymore for lupus.

    Plaquenil Uses, Dosage & Side Effects -