It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Massive hydroxychloroquine overdose Chloroquine as antiinflammatory Adverse reactions of hydroxychloroquine Hydroxychloroquine grade c pregnancy Glucose-6-phosphate dehydrogenase G6PD is an enzyme in the pentose phosphate pathway see image, also known as the HMP shunt pathway. G6PD converts glucose-6-phosphate into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of this metabolic pathway that supplies reducing energy to cells by maintaining the level of the reduced form of the co-enzyme nicotinamide adenine dinucleotide. A G6PD deficiency is an inherited disorder. It’s most common in men of African, Asian, or Mediterranean descent. It’s the result of X-linked recessive transmission, which means it’s much. Patients with G6PD deficiency, liver, or renal damage should use caution with this drug, as well as those taking digoxin, acetaminophen to avoid liver damage, and injections of botulinum toxin, which can have decreased efficacy if taken with hydroxychloroquine. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. G6pd deficiency hydroxychloroquine Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, G6PD Test Purpose, Procedure, and Follow-Up What is hydroxychloroquine used for arthritis Screening patients for glucose-6-phosphate dehydrogenase G6PD deficiency before prescribing hydroxychloroquine HCQ is unnecessary and may limit the beneficial use of the drug for individuals with systemic lupus erythematosus and other autoimmune diseases, a team of Duke rheumatology researchers reports. Does Checking G6PD Levels Before Prescribing HCQ Lead to.. Hydroxychloroquine - American Osteopathic College of.. Glucose-6-phosphate dehydrogenase deficiency - Genetics.. OBJECTIVE Some sources urge caution when prescribing hydroxychloroquine HCQ to patients with G6PDH deficiency, presumably due to a risk of hemolytic anemia. There are limited published data, however, to support this risk. G6PD deficiency is the most common enzymatic disorder of RBCs. The severity of hemolytic anemia varies among individuals with G6PD deficiency, making diagnosis more challenging in some cases. Identification of G6PD deficiency and patient education regarding safe and unsafe medications and foods is critical to preventing future episodes of. Hydroxychloroquine in G6PD Deficiency. Hydroxychloroquine Plaquenil is an oral immunomodulating medication commonly used for the the treatment of autoimmune diseases. In the world of hair loss, it is commonly used for treating lichen planopilaris, frontal fibrosing alopecia, discoid lupus and pseudopelade.