Zovirax ointment is used in the treatment of and management of genital herpes and cold sores caused due to infection with herpes simplex virus. It is prescribed to adults and adolescents as well. It is also prescribed for individuals with immune compromised conditions. The antiviral action of Zovirax ointment drug is by preventing the multiplication of the virus in the body and thereby containing the disease. This ointment does not kill the virus and hence it should not be thought of as a cure. Precautions / Side Effects For Zovirax ointment Though Zovirax ointment or Aciclovir does not cause any serious side effects, the most common side effects that many individuals experience is a burning sensation near the sore or the site of application. However, these sensations do not last long and do not occur once the body starts tolerating brand or generic Zovirax ointment. 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